Global Analysis in Isothermal Titration Calorimetry Displacement Titrations with AFFINImeter

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Isothermal titration calorimetry (ITC) displacement titrations offer an attractive alternative to standard ITC assays when working with ultra high- or ultra low- affinity interacting systems. The method requires the fitting of at least two isotherms that share various adjustable parameters. AFFINImeter counts with advanced tools, like the global fitting of multiple dataseries, which can facilitate the analysis and expand the range of applications of ITC experiments like the displacement titration.