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International Workshop on Isothermal Titration Calorimetry Developments

September 10th, 2014, Santiago de Compostela (Spain).


How to Attend the workshop on September 10th?

The format of the International Workshop on Isothermal Titration Calorimetry  consists in an OPEN DAY (September 10th)  FREE REGISTRATIONS

The open day may be attended in person at the Faculty of Physics of the University of Santiago de Compostela or online via video-streaming.

The registration to this event will end on 9th September 2014. All the on-site assistants will receive a certificate of attendance.


Latest news

  • The workshop starts on 10th September, at 9:30 am (CET, GMT+2:00)
  • The registration to this event will end on 9th September 2014.

About the workshop

Isothermal Titration Calorimetry is an extraordinarily powerful technique to obtain binding parameters from molecular interactions. This experimental technique  is currently being underutilized, inaccurately or even incorrectly employed in many cases.

The overall objective of this workshop is to evaluate the current state of both Isothermal Titration Calorimetry instruments and data analysis, as well as the perspectives for the short, medium and long term. We aim to identify common errors, making known original analysis and so new possibilities to promote the correct use of this technique. The main topics to include in this workshop are:

  • Equilibrium and kinetic modeling for the analysis of ITC data.
  • Hardware Limitations of the technique.
  • New applications of Isothermal Titration Calorimetry.
  • New tools for the analysis and optimization of the experiments.


Confirmed Speakers

Invited Researchers

  • Luis García (University of Santiago de Compostela)
  • Enrique García Hernández (National Autonomous University of Mexico)
  • Margarida Bastos (University of Porto)

AFFINImeter Scientific Department

  • Ángel Piñeiro (CSO, AFFINImeter/University of Santiago de Compostela, Spain)
  • Juan Sabín (Product Designer, AFFINImeter/University of Santiago de Compostela, Spain)
  • Eva Muñoz (Senior Scientist, AFFINImeter)

Invited Industry

  • Natalia Markova (Malvern Instruments Limited, MicroCal), Speaker
  • Luis Pablo Calle (Analytical Technologies, Lilly, Spain)


The open day will consists of 6 invited talks plus a hands on session of AFFINImeter where we will give some examples of how to perform a a rigorous Isothermal Titration Calorimetry Data Analysis.

All times are CET, GMT+2:00.

  • 9:30 - 9:45 : Welcome presentation

  • 9:45 - 11:30 : Invited speakers sessions

    • 9:50 - 10:20
      ITC: Facts and caveats
      Adrián Velázquez Campoy (University of Zaragoza)

    • 10:25-10:55
      Kinetic ITC sheds light on RNA-mediated genetic regulation
      Philippe Dumas (University of Strasbourg, France)

    • 11:00-11:30
      Incremental ITC reveals the mechanism of action of HIV-1 reverse transcriptase and inhibition mechanism by non-nucleoside inhibitors
      Eric Ennifar (University of Strasbourg, France)

  • 11:35 - 12:00 : Break

    • 12:00 - 12:20 Invited Industry: Malvern Instruments Limited (MicroCal)
      Good quality ITC data: experimental design and data analysis - two sides of the same coin
      Natalia Markova (Malvern Instruments Limited)

    • 12:25 - 12:55
      I2CITC-modular numerical analysis of ITC data for coupled equilibrium systems
      Niek Buurma (Cardiff University, UK)

    • 13:00 - 13:30
      Micellization, solution and protonation thermodynamics by Isothermal Titration Calorimetry
      Daniel Ondo (Institute of Chemical Technology, Prague)

  • 13:30 - 16:00 : Lunch

  • 16:00 - 17:10 : AFFINImeter: A new tool to analyze Isothermal Titration Calorimetry data

    • 16:00 - 16:30
      ITC Analysis with AFFINImeter: Advantages, opportunities and challenges
      Angel Piñeiro (CSO AFFINImeter/University of Santiago de Compostela)

    • 16:40 - 17:10
      New applications of Isothermal Titration Calorimetry using AFFINImeter
      Juan Sabín (Product Designer AFFINImeter/University of Santiago de Compostela)

  • 17:10 - 17:30 : Break

  • 17:30 - 19:00 : Isothermal Titration Calorimetry analysis tutorials

    • 17:30 - 17:50
      Create your own binding models using AFFINImeter
      Eva Muñoz (Senior Scientist, AFFINImeter)

    • 17:50 - 18:20
      Simulate ITC Isotherms to improve your experimental setup
      Eva Muñoz (Senior Scientist, AFFINImeter)

    • 18:20 - 19:00
      Analyze your ITC data using the advanced fitting tools of AFFINImeter
      Eva Muñoz (Senior Scientist, AFFINImeter)

  • 19:00 - 19:05 : Closing remarks
The workshop WIDEN-ITC starts September 10th at 9:30 (CET, GMT+2:00). Also, there will be a live chat room available for all online participants.

-The evening session will include a series of interactive tutorials on how to use AFFINImeter-ITC where all participants will have the chance to familiarize and practice with the software. In order to have access to AFFINImeter you will need to create a user account in http://www.affinimeter.com/app/index.php/auth/register.

-We strongly encourage you to get the AFFINImeter user account today, before the start of the workshop, to avoid last minute rush.

-With the user account you can start trying some of the functionalities of AFFINImeter and get familiarized with it before the workshop.

-If you are already a beta tester you don't need to open a new AFFINImeter account. Use your current username and password.

-Finally, on-site participants should bring their own labtops to the conference room. Please make sure the labtop´s battery is fully charged for the evening session (individual electrical outlets are not guaranteed).