Resources

AFFINImeter: A software to analyze molecular recognition processes from experimental data

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Extending ITC to Kinetics with KinITC, Methods in Enzymology, Vol. 567, Chap. 7, A.Feig Ed.

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Rigorous equations for isothermal titration calorimetry: theoretical and practical consequences

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  Cases of use

Isothermal Titration Calorimetry

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Analytical discrimination of ligands in heterogeneous mixtures with AFFINImeter. 1.07 MB

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Solving complex interactions with AFFINImeter: Competing ligands binding to a multiple site receptor. 1.60 MB

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Global Analysis in Isothermal Titration Calorimetry Displacement Titrations with AFFINImeter. 1.35 MB

Miscellaneous topics & notes

 

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How to export files from TA software to use in AFFINImeter 692.04 KB

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Quick guide for global fitting with AFFINImeter 1.94 MB

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KinITC quick guide for raw data processing and data analysis 606.96 KB

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Table of representative binding models 653.67 KB

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Stoichiometric and site constants: two approaches to analyze data with AFFINImeter. 452.49 KB

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Working with AFFINImeter models based on a stoichiometric equilibria approach. 513.25 KB

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Working with AFFINImeter models based on an independent sites approach. 493.41 KB

  Video tutorials

Our scientific team recorded these tutorials to help you get started with AFFINImeter.
You can see them all on our Youtube Channel.

 

 

 Webinars 

Widen ITC 2014

These videos are recorded broadcasts of our latest workshop: Widen ITC 2014. Also, on the workshop web page, you can find all the information related to the workshop and all videos recorded

The course of Isothermal Titration Calorimetry data analysis

Isothermal Titration Calorimetry (ITC) is widely considered the gold standard technique for the direct determination of binding thermodynamics.
Nowadays, getting kinetic information directly from the thermogram is also possible thanks to the method KinITC implemented in AFFINImeter. Besides KinITC, AFFINImeter offers a number of advanced analytical tools to take the most out of ITC data.

Aiming to show researchers how to make use of these tools, we have prepared a course on ITC data analysis, consisting of a series of video tutorials imparted by Eva Muñoz (Senior Scientist at AFFINImeter).  You can visualize the full course by clicking on the button: